| Novak Djokovic (1) | Bye | | | | | | |
| Bye | - | Novak Djokovic (1) | 6 6 | | | | |
| Kyle Edmund | 6 5 7 (8) | Kyle Edmund | 3 3 | | | | |
| Jiri Vesely | 4 7 6 (6) | | | Novak Djokovic (1) | 6 6 | | |
| Diego Schwartzman | 6 3 6 (4) | | | Joao Sousa (33) | 4 1 | | |
| Vasek Pospisil | 2 6 7 (7) | Vasek Pospisil | 7 (7) 6 (5) 2 | | | | |
| Bye | - | Joao Sousa (33) | 6 (1) 7 (7) 6 | | | | |
| Joao Sousa (33) | Bye | | | | | Novak Djokovic (1) | 6 6 |
| Feliciano Lopez (21) | Bye | | | | | Dominic Thiem (14) | 3 4 |
| Bye | - | Feliciano Lopez (21) | 4 4 | | | | |
| Yoshihito Nishioka | 6 6 | Yoshihito Nishioka | 6 6 | | | | |
| Jared Donaldson | 3 4 | | | Yoshihito Nishioka | 2 2 | | |
| Victor Estrella Burgos | 3 2 | | | Dominic Thiem (14) | 6 6 | | |
| Sam Groth | 6 6 | Sam Groth | 5 2 | | | | |
| Bye | - | Dominic Thiem (14) | 7 6 | | | | |
| Dominic Thiem (14) | Bye | | | | | | |
| Richard Gasquet (10) | Bye | | | | | | |
| Bye | - | Richard Gasquet (10) | 6 6 | | | | |
| Alejandro Gonzalez | 7 2 6 (3) | Albert Ramos-Vinolas | 4 4 | | | | |
| Albert Ramos-Vinolas | 5 6 7 (7) | | | Richard Gasquet (10) | 6 6 | | |
| Mikhail Youzhny | 6 6 | | | Benoit Paire (20) | 3 0 | | |
| Ernests Gulbis | 4 2 | Mikhail Youzhny | 3 4 | | | | |
| Bye | - | Benoit Paire (20) | 6 6 | | | | |
| Benoit Paire (20) | Bye | | | | | Richard Gasquet (10) | 4 6 5 |
| Steve Johnson (31) | Bye | | | | | Tomas Berdych (7) | 6 3 7 |
| Bye | - | Steve Johnson (31) | 7 (11) 7 (7) | | | | |
| Michael Mmoh | 6 (3) 6 (4) | Alexander Zverev | 6 (09) 6 (3) | | | | |
| Alexander Zverev | 7 (7) 7 (7) | | | Steve Johnson (31) | 3 7 (8) 3 | | |
| Rajeev Ram | 7 7 (9) | | | Tomas Berdych (7) | 6 6 (6) 6 | | |
| Evgeny Donskoy | 5 6 (7) | Rajeev Ram | | | | | |
| Bye | - | Tomas Berdych (7) | walkover | | | | |
| Tomas Berdych (7) | Bye | | | | | | |
| Horacio Zeballos | Bye | | | | | | |
| Bye | - | Horacio Zeballos | 6 6 | | | | |
| Juan Martin Del Potro | 6 7 (7) | Juan Martin Del Potro | 4 4 | | | | |
| Guido Pella | 0 6 (4) | | | Horacio Zeballos | 1 6 7 (7) | | |
| Fernando Verdasco | 7 (7) 6 | | | Fernando Verdasco | 6 4 6 (4) | | |
| Gilles Muller | 6 (2) 3 | Fernando Verdasco | 6 6 | | | | |
| Bye | - | Jeremy Chardy (28) | 4 4 | | | | |
| Jeremy Chardy (28) | Bye | | | | | Horacio Zeballos | 5 3 |
| Viktor Troicki (19) | Bye | | | | | David Goffin (15) | 7 6 |
| Bye | - | Viktor Troicki (19) | 6 (6) 7 (11) 7 (7) | | | | |
| Inigo Cervantes | 6 6 | Inigo Cervantes | 7 (8) 6 (09) 6 (3) | | | | |
| Andrey Rublev | 4 2 | | | Viktor Troicki (19) | 1 1 | | |
| Bjorn Fratangelo | 3 5 | | | David Goffin (15) | 6 6 | | |
| Marcel Granollers | 6 7 | Marcel Granollers | 4 4 | | | | |
| Bye | - | David Goffin (15) | 6 6 | | | | |
| David Goffin (15) | Bye | | | | | | |
| Marin Cilic (11) | Bye | | | | | | |
| Bye | - | Marin Cilic (11) | 6 6 | | | | |
| Dennis Novikov | 1 6 (5) | Dusan Lajovic | 4 1 | | | | |
| Dusan Lajovic | 6 7 (7) | | | Marin Cilic (11) | 3 7 (7) 3 | | |
| Ivan Dodig | 6 3 0 ret. | | | Gilles Simon (18) | 6 6 (4) 6 | | |
| Juan Monaco | 3 6 5 | Juan Monaco | 5 1 | | | | |
| Bye | - | Gilles Simon (18) | 7 6 | | | | |
| Gilles Simon (18) | Bye | | | | | Gilles Simon (18) | 6 6 |
| Guillermo Garcia-Lopez (32) | Bye | | | | | Lucas Pouille | 0 1 |
| Bye | - | Guillermo Garcia-Lopez (32) | 2 4 | | | | |
| Teymuraz Gabashvili | 5 3 | Lucas Pouille | 6 6 | | | | |
| Lucas Pouille | 7 6 | | | Lucas Pouille | 6 (1) 7 (7) 7 | | |
| Taylor Fritz | 6 6 | | | David Ferrer (8) | 7 (7) 6 (4) 5 | | |
| Simone Bolelli | 4 2 | Taylor Fritz | 6 (6) 1 | | | | |
| Bye | - | David Ferrer (8) | 7 (8) 6 | | | | |
| David Ferrer (8) | Bye | | | | | | |
| Rafael Nadal (5) | Bye | | | | | | |
| Bye | - | Rafael Nadal (5) | 6 4 0 ret. | | | | |
| Damir Dzumhur | 4 6 6 | Damir Dzumhur | 2 6 3 | | | | |
| Leonardo Mayer | 6 3 4 | | | Damir Dzumhur | 4 6 6 | | |
| Brian Baker | 4 2 | | | Mikhail Kukushkin | 6 1 2 | | |
| Mikhail Kukushkin | 6 6 | Mikhail Kukushkin | 5 6 | | | | |
| Bye | - | Thomaz Bellucci (30) | 7 3 ret. | | | | |
| Thomaz Bellucci (30) | Bye | | | | | Damir Dzumhur | 0 3 |
| Jack Sock (22) | Bye | | | | | Milos Raonic (12) | 6 6 |
| Bye | - | Jack Sock (22) | 6 3 | | | | |
| Nicolas Jarry | 6 (7) 5 | Sergiy Stakhovsky | 2 2 ret. | | | | |
| Sergiy Stakhovsky | 7 (9) 7 | | | Jack Sock (22) | 6 (3) 4 | | |
| Hyeon Chung | 3 6 1 | | | Milos Raonic (12) | 7 (7) 6 | | |
| Denis Kudla | 6 3 6 | Denis Kudla | 6 (4) 4 | | | | |
| Bye | - | Milos Raonic (12) | 7 (7) 6 | | | | |
| Milos Raonic (12) | Bye | | | | | | |
| John Isner (13) | Bye | | | | | | |
| Bye | - | John Isner (13) | 2 6 6 (5) | | | | |
| Tommy Paul | 4 7 5 | Tim Smyczek | 6 2 7 (7) | | | | |
| Tim Smyczek | 6 5 7 | | | Tim Smyczek | 4 4 | | |
| Marcos Baghdatis | 6 6 | | | Nick Kyrgios (24) | 6 6 | | |
| Benjamin Becker | 3 4 | Marcos Baghdatis | 2 1 | | | | |
| Bye | - | Nick Kyrgios (24) | 6 6 | | | | |
| Nick Kyrgios (24) | Bye | | | | | Nick Kyrgios (24) | 7 (7) 6 |
| Sam Querrey (29) | Bye | | | | | Andrey Kuznetsov | 6 (3) 3 |
| Bye | - | Sam Querrey (29) | 7 (7) 2 4 | | | | |
| Adrian Mannarino | 2 6 6 | Adrian Mannarino | 6 (5) 6 6 | | | | |
| Illya Marchenko | 6 2 3 | | | Adrian Mannarino | 6 5 0 | | |
| Rogerio Dutra Silva | 2 3 | | | Andrey Kuznetsov | 2 7 6 | | |
| Andrey Kuznetsov | 6 6 | Andrey Kuznetsov | 6 6 | | | | |
| Bye | - | Stan Wawrinka (4) | 4 3 | | | | |
| Stan Wawrinka (4) | Bye | | | | | | |
| Kei Nishikori (6) | Bye | | | | | | |
| Bye | - | Kei Nishikori (6) | 6 7 (7) | | | | |
| Pierre-Hugues Herbert | 7 6 | Pierre-Hugues Herbert | 2 6 (4) | | | | |
| Lukas Rosol | 5 4 | | | Kei Nishikori (6) | 6 6 | | |
| Andreas Seppi | 6 6 | | | Alexandr Dolgopolov (27) | 2 2 | | |
| Donald Young | 3 1 | Andreas Seppi | 4 4 | | | | |
| Bye | - | Alexandr Dolgopolov (27) | 6 6 | | | | |
| Alexandr Dolgopolov (27) | Bye | | | | | Kei Nishikori (6) | 6 6 |
| Roberto Bautista Agut (17) | Bye | | | | | Roberto Bautista Agut (17) | 2 4 |
| Bye | - | Roberto Bautista Agut (17) | 7 2 | | | | |
| Roberto Carballes Baena | 6 2 3 | Aljaz Bedene | 5 2 ret. | | | | |
| Aljaz Bedene | 4 6 6 | | | Roberto Bautista Agut (17) | 2 6 7 (7) | | |
| Paul-Henri Mathieu | 2 6 3 | | | Jo-Wilfried Tsonga (9) | 6 3 6 (3) | | |
| Santiago Giraldo | 6 2 6 | Santiago Giraldo | 3 1 | | | | |
| Bye | - | Jo-Wilfried Tsonga (9) | 6 6 | | | | |
| Jo-Wilfried Tsonga (9) | Bye | | | | | | |
| Gael Monfils (16) | Bye | | | | | | |
| Bye | - | Gael Monfils (16) | 6 6 | | | | |
| Nicolas Mahut | 6 (3) 2 | Tatsuma Ito | 3 2 | | | | |
| Tatsuma Ito | 7 (7) 6 | | | Gael Monfils (16) | 6 6 | | |
| Pablo Carreno Busta | 3 2 | | | Pablo Cuevas (23) | 3 4 | | |
| John Millman | 6 6 | John Millman | 5 4 | | | | |
| Bye | - | Pablo Cuevas (23) | 7 6 | | | | |
| Pablo Cuevas (23) | Bye | | | | | Gael Monfils (16) | 6 (5) 6 6 |
| Grigor Dimitrov (26) | Bye | | | | | Grigor Dimitrov (26) | 7 (7) 3 3 |
| Bye | - | Grigor Dimitrov (26) | 7 (10) 4 6 | | | | |
| Elias Ymer | 1 6 3 | Federico Delbonis | 6 (08) 6 4 | | | | |
| Federico Delbonis | 6 4 6 | | | Grigor Dimitrov (26) | 6 (1) 6 6 | | |
| Borna Coric | 6 5 5 | | | Andy Murray (2) | 7 (7) 4 3 | | |
| Denis Istomin | 4 7 7 | Denis Istomin | 3 5 | | | | |
| Bye | - | Andy Murray (2) | 6 7 | | | | |
| Andy Murray (2) | Bye | | | | | | |
